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A clinical application of iodine quantitation using digital fluorography
W D Thompson1, C J Kotre, J P Owen
1Department of Radiology, North Tees General Hospital, Stockton on Tees.
The British Journal of Radiology
|November 1, 1990
Summary
Digital fluoroscopy enables iodine quantitation in the urinary tract, offering new insights into kidney function. This method accurately measured iodine levels in most kidneys, showing potential for assessing conditions like dilated upper urinary tracts.
Area of Science:
- Radiology
- Medical Imaging
- Urology
Background:
- Intravenous urography is a common diagnostic tool.
- Quantitative assessment of renal function can be challenging.
- Digital fluoroscopy offers potential for advanced imaging analysis.
Purpose of the Study:
- To evaluate a novel method for in vitro iodine quantitation using digital fluoroscopy.
- To assess the feasibility of applying this technique to intravenous urograms.
- To explore potential clinical applications for quantitative urinary tract imaging.
Main Methods:
- A preliminary clinical study involving 20 patients undergoing intravenous urography.
- Application of digital fluoroscopy for in vitro iodine quantitation.
- Measurement of iodine levels as mass thickness in renal parenchyma and collecting systems.
- Plotting variations of iodine mass thickness over time.
Main Results:
- Successful iodine quantitation achieved in 38 out of 40 kidneys (95%).
- Measurements were performed in both renal parenchyma and collecting systems.
- Subtraction artifacts due to bowel gas movement caused measurement failure in two kidneys.
- Iodine mass thickness variations over time showed patterns similar to dynamic CT and MRI studies.
Conclusions:
- Digital fluoroscopy allows for quantitative assessment of iodine in the urinary tract.
- The method shows promise for functional assessment, particularly in dilated upper urinary tracts.
- This technique provides valuable quantitative data beyond traditional anatomical imaging.