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Related Concept Videos

Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...

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Related Experiment Video

Updated: May 22, 2026

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
12:23

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

[Optical coherence tomography in multiple sclerosis].

Ángela Vidal-Jordana1, Jaume Sastre-Garriga, Xavier Montalban

  • 1Unidad de Neuroinmunología Clínica, Centre d'Esclerosi Múltiple de Catalunya (CEM-Cat), Hospital Universitari Vall d'Hebron, Barcelona, España. angela.vidal@sen.es

Revista De Neurologia
|April 26, 2012
PubMed
Summary
This summary is machine-generated.

Optical coherence tomography (OCT) can measure retinal nerve fiber layer (RNFL) thickness, offering insights into multiple sclerosis (MS). Studies show RNFL thinning in MS patients, potentially correlating with neurological disability.

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Last Updated: May 22, 2026

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12:23

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Thinned-skull Cortical Window Technique for In Vivo Optical Coherence Tomography Imaging

Published on: November 19, 2012

Area of Science:

  • Ophthalmology and Neurology
  • Neuroscience

Context:

  • Optical coherence tomography (OCT) is a non-invasive imaging technique visualizing retinal layers.
  • The retinal nerve fiber layer (RNFL), composed of ganglionic cell axons, is part of the central nervous system.
  • Emerging research explores OCT's utility in neurology, particularly for multiple sclerosis (MS).

Purpose:

  • To review studies on RNFL thickness in multiple sclerosis (MS) patients using OCT.
  • To assess the relationship between RNFL thickness and neurological disability or brain atrophy in MS.
  • To evaluate OCT's potential role in understanding, monitoring, and managing MS.

Summary:

  • OCT reveals decreased RNFL thickness in MS patients, irrespective of optic neuritis involvement, compared to controls.
  • Studies indicate an inverse correlation between RNFL thickness and neurological disability or cerebral atrophy in MS.
  • While correlations are sometimes weak and contradictory, OCT shows promise for MS understanding and monitoring.

Impact:

  • OCT provides a non-invasive method to assess potential neurological changes associated with MS.
  • RNFL thickness measurement may serve as a biomarker for disease progression or severity in MS.
  • Further research is needed to clarify OCT's role in MS management and patient outcomes.