Related Experiment Video
Updated: May 22, 2026

12:48
A Time-lapse, Label-free, Quantitative Phase Imaging Study of Dormant and Active Human Cancer Cells
Published on: February 16, 2018
Quantitative phase contrast optimised cancerous cell differentiation via ptychography
Daniel Claus1, Andrew M Maiden, Fucai Zhang
1Kroto Research Institute, University of Sheffield,S3 7HQ, Sheffield, UK. d.claus@sheffield.ac.uk
Optics Express
|April 27, 2012
Abstract:
This paper shows that visible-light ptychography can be used to distinguish quantitatively between healthy and tumorous unstained cells. Advantages of ptychography in comparison to conventional phase-sensitive imaging techniques are highlighted. A novel procedure to automatically refocus ptychographic reconstructions is also presented, which improves quantitative analysis.

