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Related Experiment Video

Updated: May 22, 2026

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

Published on: January 15, 2013

Spectroscopic polarization-sensitive full-field optical coherence tomography.

Arnaud Dubois¹

¹Laboratoire Charles Fabry, Institut d’Optique, CNRS UMR 8501, Univ Paris-Sud, 2 avenue Augustin Fresnel, 91127 Palaiseau, France. arnaud.dubois@institutoptique.fr

|April 27, 2012

Summary

Full-field optical coherence tomography (FF-OCT) offers high-resolution imaging. A new multimodal FF-OCT system simultaneously measures intensity, power spectrum, and phase-retardation for enhanced imaging contrast.

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Area of Science:

Biomedical Optics
Optical Imaging
Interference Microscopy

Background:

Full-field optical coherence tomography (FF-OCT) is an advanced imaging technique utilizing low-coherence interference microscopy.
FF-OCT provides approximately 1 µm spatial resolution for semi-transparent samples.
It generates en-face tomographic images by combining interferometric data from an array camera.

Purpose of the Study:

To introduce and demonstrate a novel multimodal FF-OCT system.
To showcase the system's capability for simultaneous measurement of multiple optical properties.
To evaluate the system's performance in terms of imaging contrast and complexity.

Main Methods:

Development of a multimodal FF-OCT system integrating intensity, power spectrum, and phase-retardation measurements.
Acquisition of interferometric images using an array camera.
Arithmetic combination of acquired images to produce tomographic data.

Main Results:

The multimodal FF-OCT system successfully acquired simultaneous measurements of intensity, power spectrum, and phase-retardation.
Enhanced imaging contrasts were achieved compared to conventional FF-OCT.
The system demonstrated moderate increases in experimental complexity and cost.

Conclusions:

The developed multimodal FF-OCT system offers a significant advancement in optical imaging.
Simultaneous measurement of multiple optical parameters enhances imaging contrast for semi-transparent samples.
This technology presents a promising tool for detailed sample analysis with improved visualization.