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Updated: May 22, 2026

Breathing-controlled Electrical Stimulation (BreEStim) for Management of Neuropathic Pain and Spasticity
Published on: January 10, 2013
Breathing-controlled electrical stimulation could modify the affective component of neuropathic pain after
Sheng Li1, Danielle H Melton, Jeffrey C Berliner
1Department of Physical Medicine and Rehabilitation, University of Texas Medical School - Houston, Houston, TX.
Abstract:
In this case, a 31-year-old male suffered phantom neuropathic pain for more than 3 years after an above-the-knee amputation. His shooting phantom pain disappeared after the first session of breathing-controlled electrical stimulation, and reappeared or was triggered 28 days after an experimental error during which he received sustained electrical stimulation. In other words, painful shooting stimuli may not have been "cured" but forgotten and retriggered by a fearful event due to the experimental error. Therefore, this accidental finding provides a unique opportunity to understand sensory and affective components of neuropathic pain, and a novel intervention could modify the affective component of it.

