Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Depressive Disorders: Etiology

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

Depression: Overview

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...

Socioemotional Development during Infancy

Socioemotional Development during Infancy

Socio-emotional development in infancy is primarily shaped by early emotional responses and social connections, with temperament playing a central role. Temperament refers to the consistent patterns in an individual's emotional and behavioral responses, observable even in infancy. By examining temperament, researchers can better understand an infant's unique ways of interacting with the world, influencing subsequent personality and socio-emotional growth.
Primary Temperament Types
Stella Chess...

Long-term Depression

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.

Long-term Depression

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over time, all...

Sources of Self-Esteem I: Family Experience

Sources of Self-Esteem I: Family Experience

Self-esteem, a crucial component of psychological development, is significantly shaped by familial experiences. The early parent-child relationship serves as a foundational influence on a child's self-concept, with long-lasting effects extending into adolescence and adulthood.Parental Behaviors and Early Self-Esteem FormationEmpirical studies have identified four principal parental behaviors that foster healthy self-esteem in children. These include expressions of acceptance, affection, and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Future directions in depression prevention.

Journal of consulting and clinical psychology·2025

Same author

A whole-of-society approach to depression prevention during the global pandemic: Preliminary data from three large-scale trials.

Journal of consulting and clinical psychology·2025

Same author

Adaptation of an evidence-based, preventive intervention to promote mental health in Hispanic adolescents: eHealth Familias Unidas Mental Health.

Translational behavioral medicine·2024

Same author

Macro- and Microstructural White Matter Differences in Neurologic Postacute Sequelae of SARS-CoV-2 Infection.

AJNR. American journal of neuroradiology·2024

Same author

Time Trends in Adolescent Diagnoses of Major Depressive Disorder and Co-occurring Psychiatric Conditions in Electronic Health Records.

Research square·2024

Same author

Cognitive behavioral program for the prevention of depression in at-risk adolescents: isolating the effects of dose.

American journal of epidemiology·2024

Search research articles

Related Experiment Video

Updated: May 22, 2026

Chronic Social Defeat Stress in Early Adolescent Male Mice

Chronic Social Defeat Stress in Early Adolescent Male Mice

Published on: January 24, 2025

Developmental risk of depression: experience matters.

William R Beardslee¹, Tracy R G Gladstone, Erin E O'Connor

¹Department of Psychiatry, Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA. william.beardslee@childrens.harvard.edu

Child and Adolescent Psychiatric Clinics of North America

|April 28, 2012

Summary

Understanding youth depression risks is crucial. This review highlights environmental factors that build resilience in children and adolescents, informing prevention strategies.

More Related Videos

A New Method for Inducing a Depression-Like Behavior in Rats

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

Related Experiment Videos

Last Updated: May 22, 2026

Chronic Social Defeat Stress in Early Adolescent Male Mice

Chronic Social Defeat Stress in Early Adolescent Male Mice

Published on: January 24, 2025

A New Method for Inducing a Depression-Like Behavior in Rats

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

Area of Science:

Child and Adolescent Psychiatry
Developmental Psychology
Mental Health Research

Background:

Youth depression is a significant public health concern.
Identifying risk factors is essential for effective intervention.
Environmental influences play a critical role in mental health outcomes.

Purpose of the Study:

To review current literature on risk factors for depression onset in youth.
To examine the role of environmental factors in fostering resilience.
To emphasize the need for prevention strategies targeting resiliency.

Main Methods:

Literature review of existing research on youth depression.
Analysis of specific and nonspecific risk factors.
Synthesis of findings on environmental influences and resilience.

Main Results:

Specific risk factors include family history of depression.
Nonspecific risk factors encompass poverty and stressful life events.
Environmental factors are key in promoting resilience against depression.

Conclusions:

Early identification of risk factors is vital for prevention.
Interventions should focus on enhancing resilience in children and adolescents.
A comprehensive approach addressing environmental factors is necessary for youth mental health.