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Related Concept Videos

Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
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Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...
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Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
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iPS Cell Differentiation

The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.

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Related Experiment Video

Updated: May 22, 2026

Repair of a Critical-sized Calvarial Defect Model Using Adipose-derived Stromal Cells Harvested from Lipoaspirate
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Adipocyte-derived stem cells for the face.

Cynthia A Boxrud1

  • 1Oculoplastic and Reconstructive Surgery, David Geffen School of Medicine, UCLA/JSEI, 100 Stein Plaza UCLA, Los Angeles, CA 90095-7000, USA. cboxrudmd@aol.com

Facial Plastic Surgery Clinics of North America
|April 28, 2012
PubMed
Summary

This review covers fat transplantation using adipose-derived stem cells for facial rejuvenation. It presents current technologies and procedures for enhancing facial appearance.

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Area of Science:

  • Regenerative Medicine
  • Aesthetic Surgery

Background:

  • Fat transplantation is a widely used procedure in aesthetic surgery.
  • Adipose-derived stem cells (ASCs) play a crucial role in the success of fat grafts.
  • Understanding the current state of fat transplantation is essential for advancing facial rejuvenation techniques.

Purpose of the Study:

  • To provide a comprehensive overview of the current advancements in fat transplantation.
  • To highlight the role of adipose-derived stem cells in fat grafting.
  • To review existing technologies and procedures for facial rejuvenation using fat transplantation.

Main Methods:

  • Literature review of current scientific publications on fat transplantation and ASCs.
  • Analysis of technologies and procedural techniques employed in facial rejuvenation.
  • Synthesis of information regarding the efficacy and outcomes of fat grafting.

Main Results:

  • Fat transplantation utilizing ASCs shows significant potential for facial rejuvenation.
  • Current technologies offer various methods for fat harvesting, processing, and transplantation.
  • The review summarizes key procedural aspects and their impact on aesthetic outcomes.

Conclusions:

  • Fat transplantation, particularly with ASCs, is a promising approach for facial rejuvenation.
  • Continued research and technological development are expected to further enhance outcomes.
  • The presented overview serves as a foundation for future studies and clinical applications.