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Updated: May 22, 2026

Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile
Published on: October 30, 2018
Sodium methoxide: a simple but highly efficient catalyst for the direct amidation of esters
Takashi Ohshima1, Yukiko Hayashi, Kazushi Agura
1Graduate School of Pharmaceutical Sciences, Kyushu University and CREST, JST, Fukuoka, Japan. ohshima@phar.kyushu-u.ac.jp
Abstract:
A simple NaOMe catalyst provides superior accessibility to a wide variety of functionalized amides including peptides through direct amination of esters in an atom-economical and environmentally benign way.
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