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Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

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Published on: June 2, 2014

New daily persistent headache.

Randolph W Evans1

  • 1Baylor College of Medicine, Houston, TX 77004, USA. rwevans@pol.net

Headache
|May 1, 2012
PubMed
Summary
This summary is machine-generated.

New daily persistent headache is a rare disorder causing daily, unremitting headaches lasting over 4 hours. Diagnosis is by exclusion, and treatment is empiric, often mirroring chronic migraine therapies.

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Area of Science:

  • Neurology
  • Headache Medicine

Background:

  • New daily persistent headache (NDPH) is a rare disorder characterized by daily, unremitting headaches.
  • Onset typically occurs within 3 days, with headaches lasting 4 hours or more daily.

Purpose of the Study:

  • To describe the clinical features, potential triggers, and management of primary new daily persistent headache.
  • To highlight the diagnostic challenges and current treatment approaches for NDPH.

Main Methods:

  • This is a descriptive study based on the provided abstract.
  • Diagnosis is established through exclusion of secondary headache causes.

Main Results:

  • Headaches are daily and unremitting, often generalized, but can be unilateral or localized.
  • Potential triggers include infections (15%), stress (10%), or surgery (10%). Migraine features are present in over 50% of cases.
  • Most patients experience persistent headaches, with spontaneous remission in 15% and a relapsing-remitting course in 8%.

Conclusions:

  • Primary NDPH is a challenging diagnosis of exclusion with unknown pathophysiology.
  • Empiric preventive treatments are used, often adapted from chronic migraine or tension-type headache protocols.
  • Further research is needed to understand NDPH pathophysiology and develop targeted therapies.