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Related Concept Videos

Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

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Hand hygiene

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Hand washing...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
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Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...

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Updated: May 22, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

[Pustular psoriasis].

H Bachelez1

  • 1Service de Dermatologie, Hôpital Saint-Louis, 1 avenue Claude-Vellefaux, 75475 Paris cedex 10, France. herve.bachelez@sls.aphp.fr

Annales De Dermatologie Et De Venereologie
|May 1, 2012
PubMed
Summary
This summary is machine-generated.

Psoriasis pustular forms, characterized by aseptic pustules, are clinically diverse but share common features. Recent genetic and molecular insights are redefining their role in inflammatory skin and systemic diseases.

Related Experiment Videos

Last Updated: May 22, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Area of Science:

  • Dermatology
  • Immunology
  • Genetics

Context:

  • Pustular psoriasis encompasses clinically heterogeneous subtypes.
  • Aseptic pustular lesions are a common diagnostic feature across these forms.
  • Understanding pustular psoriasis is crucial for classifying inflammatory skin conditions.

Purpose:

  • To review the clinical heterogeneity of pustular psoriasis.
  • To explore the relationship between pustular and plaque psoriasis (psoriasis vulgaris).
  • To discuss updated genetic and molecular mechanisms driving pustular psoriasis.

Summary:

  • Pustular psoriasis presents diverse clinical manifestations unified by aseptic pustules.
  • Recent advances in genetics and molecular biology are clarifying disease mechanisms.
  • The study highlights the need to reconsider pustular psoriasis within broader inflammatory disease categories.

Impact:

  • This research reframes pustular psoriasis as a significant entity in cutaneous and systemic inflammatory diseases.
  • Updated genetic and molecular data offer new avenues for therapeutic strategies.
  • Reclassification may improve diagnostic accuracy and patient management for inflammatory conditions.