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Updated: May 22, 2026
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Continuous Video Electroencephalogram during Hypoxia-Ischemia in Neonatal Mice
Published on: June 11, 2020
A study on voiding pattern of newborns with hypoxic ischemic encephalopathy
1Pediatric Urodynamic Center and Department of Urology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. wenjg@hotmail.com
Urology
|May 1, 2012
Summary
Hypoxic ischemic encephalopathy (HIE) significantly alters voiding patterns in preterm newborns, leading to lower voided volumes and reduced consciousness during urination. These changes highlight the impact of HIE on the central nervous system
Area of Science:
- Neonatal Medicine
- Neurology
- Pediatrics
Background:
- Hypoxic ischemic encephalopathy (HIE) is a serious birth complication affecting newborns.
- Understanding the neurological impact of HIE on physiological functions like voiding is crucial for patient care.
Purpose of the Study:
- To compare the voiding patterns of preterm newborns with and without HIE.
- To investigate the influence of HIE on voiding parameters and consciousness during urination.
Main Methods:
- A study involving 40 hospitalized preterm newborns (21 with HIE, 19 without).
- Recorded voided volume, postvoid residual (PVR) volume, consciousness at voiding (via EEG), voiding frequency, and fluid intake over 4 hours.
- Voided volume measured by diaper weight difference; PVR by ultrasound.
Main Results:
- Newborns with HIE exhibited significantly lower voided volumes and reduced consciousness during voiding compared to controls.
- Conversely, newborns with HIE showed significantly higher PVR volumes and increased voiding frequency.
- Fluid intake was standardized across both groups.
Conclusions:
- The observed differences in voiding patterns suggest the involvement of higher central nervous system centers in voiding control.
- HIE significantly impacts the voiding patterns of preterm newborns, underscoring neurological effects.
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