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Updated: May 22, 2026
14:39
Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
[Management of acute asthma]
F Saulnier1, S Préau, T Onimus
1Service de réanimation médicale et d'urgence respiratoire, hôpital Calmette, CHRU de Lille, boulevard du Professeur-Leclerc, Lille cedex, France. fabienne.saulnier@chru-lille.fr
Revue Des Maladies Respiratoires
|May 1, 2012
Summary
Asthma exacerbations can be fatal. Recognizing severity and providing prompt treatment, including oxygen, bronchodilators, and corticosteroids, is crucial for managing severe asthma attacks and preventing mortality.
Area of Science:
- Pulmonology
- Critical Care Medicine
- Emergency Medicine
Context:
- Asthma exacerbations pose a significant risk to patients.
- Mortality often stems from underestimating severity and delayed/inadequate treatment.
- Understanding lung mechanics and cardiopulmonary interactions is key to assessing exacerbation severity.
Purpose:
- To review the management of acute severe and near-fatal asthma.
- To outline essential therapeutic goals: oxygenation, bronchodilators, and corticosteroids.
- To discuss mechanical ventilation strategies and adjunctive therapies for critical cases.
Summary:
- Effective management involves prompt assessment of severity and appropriate in-hospital care.
- Key treatments include oxygen, inhaled bronchodilators, and systemic corticosteroids.
- Mechanical ventilation with permissive hypercapnia is reserved for near-fatal attacks.
Impact:
- Asthma-related mortality has decreased, but many deaths remain preventable.
- Adopting a proactive approach where every exacerbation is considered potentially fatal is recommended.
- Enhanced patient and healthcare provider education is vital for improving outcomes.
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