Quality of life after children undergo a radical arterial switch operation at an older age

Jing-bin Huang1, Yong-tao Cao, Jian Liang

  • 1Department of Cardiothoracic Surgery, Affiliated Ruikang Hospital of Guangxi Traditional Chinese Medical College, Nanning, Guangxi Zhuang Autonomous Region, China. gz98039@hotmail.com

Insights

Children undergoing arterial switch operation (ASO) after 6 months of age show acceptable quality of life, comparable to healthy peers. This study evaluated long-term outcomes using the Pediatric Quality of Life Inventory (PedsQL).

Area of Science:

  • Pediatric Cardiology
  • Congenital Heart Disease Surgery
  • Quality of Life Research

Background:

  • The arterial switch operation (ASO) is a critical intervention for congenital heart defects like transposition of the great arteries.
  • Evaluating long-term quality of life in pediatric cardiac surgery patients is essential for comprehensive patient care.
  • Previous studies have focused on early ASO; outcomes for later corrective ASO require further investigation.

Purpose of the Study:

  • To assess the health-related quality of life in children who underwent a corrective arterial switch operation (ASO) at an older age (>6 months).
  • To compare the quality of life scores of these patients with a healthy pediatric population.

Main Methods:

  • Retrospective review of 86 patients with complete transposition of the great arteries, ventricular septal defect, or Taussig-Bing anomaly and severe pulmonary hypertension.
  • Focus on patients who underwent corrective ASO at >6 months of age between May 2000 and October 2008.
  • Health-related quality of life evaluated using the Pediatric Quality of Life Inventory (PedsQL) version 4.0 in 80 survivors.

Main Results:

  • The study included 80 survivors with a mean follow-up of 3.5 years; mean age at last visit was 7.0 years.
  • Patients demonstrated acceptable scores across all PedsQL scales.
  • Quality of life scores were comparable to those of a healthy pediatric population.

Conclusions:

  • Corrective arterial switch operation (ASO) performed at an older age (>6 months) yields acceptable long-term quality of life for children.
  • Outcomes suggest that surgical correction later in infancy does not negatively impact quality of life compared to healthy children in China.
Abstract

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