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Updated: May 22, 2026

Puncture-Induced Iris Neovascularization as a Mouse Model of Rubeosis Iridis
Published on: March 8, 2018
Nematode-induced low-grade chronic inflammation of the iris
1VA NIHCS Eye Clinic, 2121 Lake Ave., Fort Wayne, IN 46805, USA. wendy.moyle@va.gov
Purpose:
There are thousands of parasitic nematode species that have been identified. Many have been documented to invade the eye and periorbital tissues. Whether adult or larvae, alive or dead, they can result in a wide range of ocular and systemic manifestations. Classification of the nematode can be helpful in the treatment planning for these patients.
Case Report:
A 60-year-old Hispanic male presented without complaints. During routine examination, the presence of peripheral anterior synechiae, posterior synechiae, and focal cataract were linked to an immobile, partly degenerated 2 to 3 mm long coiled nematode in the anterior chamber.
Conclusion:
Results from DNA analysis were most consistent with a member of the Trichostrongylus or Metastrongylus genera, or a new nematode species.
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