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Updated: May 22, 2026
06:40
The Dyspepsia Educational Tool As a Novel Aid in Dyspepsia Management
Published on: June 29, 2019
[Association between dyspepsia and upper endoscopic findings].
Hye-Kyung Jung1, Seong-Eun Kim, Ki-Nam Shim
1Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea. junghk@ewha.ac.kr
Summary
Approximately 40% of individuals undergoing endoscopy show significant findings. Dyspepsia symptoms alone do not reliably predict these abnormalities, but Rome III criteria for functional dyspepsia may help rule them out.
Area of Science:
- Gastroenterology
- Clinical Medicine
- Diagnostic Endoscopy
Context:
- Dyspeptic symptoms are common reasons for upper gastrointestinal endoscopy.
- Predicting significant endoscopic findings based on symptoms is clinically relevant.
- A large cohort of 3,872 subjects undergoing endoscopy was analyzed.
Purpose:
- To determine the prevalence of significant endoscopic findings in patients with dyspepsia.
- To assess the association between dyspeptic symptoms and endoscopic results.
- To identify predictors of significant endoscopic findings.
Summary:
- 39.1% of subjects had significant endoscopic findings (e.g., peptic ulcer disease, reflux esophagitis, gastric cancer).
- No significant difference in findings between dyspepsia and asymptomatic groups; however, peptic ulcer was more common with reflux symptoms.
- Male gender increased risk (OR 3.91), while Rome III functional dyspepsia criteria decreased risk (OR 0.75).
Impact:
- Findings suggest dyspepsia symptoms may not strongly predict significant endoscopic abnormalities.
- Rome III criteria for functional dyspepsia may aid in identifying patients unlikely to have significant upper endoscopic findings.
- This research informs diagnostic strategies for upper gastrointestinal endoscopy.
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