Related Experiment Video
Updated: May 22, 2026

05:53
Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
Published on: June 21, 2018
Genetic testing in domestic cats.
1Department of Population Health & Reproduction, School of Veterinary Medicine, University of California - Davis, Davis, CA 95616, USA. lalyons@ucdavis.edu
Molecular and Cellular Probes
|May 2, 2012
Summary
Genetic testing for domestic cats aids veterinary care, breed management, and forensics. DNA analysis identifies specific genes, mutations, and individual cat identities for various scientific applications.
Area of Science:
- Genetics
- Veterinary Science
- Forensic Science
Background:
- Numerous genetic tests are available for domestic cats.
- These tests support veterinary health care, breed management, species identification, and forensic investigations.
- Over fifty mutations in approximately thirty-five genes are known to cause feline health issues or affect appearance.
Purpose of the Study:
- To review the various genetic tests available for the domestic cat.
- To discuss the applications of these genetic tests in different scientific fields.
- To highlight genetic tests specific to individual cats and their genomes.
Main Methods:
- Analysis of genes and mutations associated with feline health and appearance.
- Utilizing specific gene knock-outs (e.g., sweet and drug receptors) and mtDNA markers for species identification.
- Employing Short Tandem Repeat (STR) and Single Nucleotide Polymorphism (SNP) panels for differentiating race, breed, individual identity, and sex.
Main Results:
- Genetic tests can identify over fifty mutations across thirty-five genes linked to feline health and appearance.
- Specific gene knock-outs and mtDNA markers facilitate accurate species identification.
- STR and SNP panels effectively distinguish cat race, breed, individual identity, and sex.
Conclusions:
- Genetic testing is a valuable tool in veterinary medicine, breed management, and forensic science for domestic cats.
- These tests provide crucial information about an individual cat's genome, health, and identity.
- Commercial availability of cat genetic tests enables accessibility for veterinarians and cat owners alike.
Related Concept Videos
Incomplete Dominance
Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.
Test Cross
Alleles are different forms of the same gene. Humans and other diploid organisms inherit two alleles of every gene, one from each parent.
Genetic Screens
Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...
Animal Mitochondrial Genetics
Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
Karyotyping
Overview
Karyotyping
Overview
