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Updated: May 22, 2026

Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth
Published on: February 9, 2012
Quantitative imaging of nonlinear shear modulus by combining static elastography and shear wave elastography
Abstract:
The study of new tissue mechanical properties such as shear nonlinearity could lead to better tissue characterization and clinical diagnosis. This work proposes a method combining static elastography and shear wave elastography to derive the nonlinear shear modulus by applying the acoustoelasticity theory in quasi-incompressible soft solids. Results demonstrate that by applying a moderate static stress at the surface of the investigated medium, and by following the quantitative evolution of its shear modulus, it is possible to accurately and quantitatively recover the local Landau (A) coefficient characterizing the shear nonlinearity of soft tissues.
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