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BK potassium channel modulation by leucine-rich repeat-containing proteins

Jiusheng Yan1, Richard W Aldrich

  • 1Section of Neurobiology, Center for Learning and Memory, University of Texas, Austin, TX 78712, USA. jshyan@mail.utexas.edu

Proceedings of the National Academy of Sciences of the United States of America
|May 2, 2012
PubMed
Summary

Researchers discovered new auxiliary subunits, LRRC52, LRRC55, and LRRC38, that modify large-conductance, voltage- and calcium-activated potassium (BK) channel function. These proteins, distinct from beta subunits, form a new gamma family regulating BK channel gating across tissues.

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