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Updated: May 22, 2026

Selective Harvesting of Marginating-pulmonary Leukocytes
Published on: March 11, 2016
Leukoreduction in patients with severe pertussis with hyperleukocytosis
Gonzalo Oñoro1, Alberto García Salido, Ignacio Mastro Martínez
1Pediatric Intensive Care Unit, Hospital Infantil Universitario Niño Jesús, Madrid, Spain. gonorootero@hotmail.com
Abstract:
When pertussis is associated with hyperleukocytosis, mortality approaches to 80%. Immature leukocytes have been identified in pulmonary arterioles, small arteries and venules. Techniques aimed at reducing leukocyte mass might improve the prognosis of these patients. We report our experience with 3 patients in whom a leukoreduction was performed in the context of severe pertussis and hyperleukocytosis.
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