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Updated: May 22, 2026

06:35
Ultrasound Assessment of Endothelial Function: A Technical Guideline of the Flow-mediated Dilation Test
Published on: April 27, 2016
[Correction of endothelial dysfunction by L-arginine under experimental pre-eclampsia conditions]
Eksperimental'Naia I Klinicheskaia Farmakologiia
|May 4, 2012
Abstract:
The ADMA-like pre-eclampsia in pregnant rats was modeled by daily introduction of L-NAME in a dose of 25 mg/kg for 7 days. L-arginine (200 mg/kg) prevented the development of arterial hypertension and a decrease in placentary microcirculation and microalbuminuria. The possibility of using L-arginine for the prevention of competitive eNOS inhibition by ADMA is discussed.
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