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Updated: May 22, 2026

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems
Published on: May 2, 2025
Do patient and nurse outcome differences exist between 2 negative pressure wound therapy systems?
Nancy M Albert1, Ronald Rock, Mary Ann Sammon
1Nursing Institute, Cleveland Clinic, Ohio 44195, USA. albertn@ccf.org
Foam and gauze negative pressure wound therapy (NPWT) systems showed similar effectiveness in healing, pain management, and cost. Nurses also reported comparable ease of use and time for dressing changes between the two NPWT types.
Area of Science:
- Wound Care
- Medical Devices
- Clinical Trials
Background:
- Negative pressure wound therapy (NPWT) is a widely used treatment for various wound types.
- Foam and gauze dressings are common components of NPWT systems, but their comparative effectiveness is not fully established.
Purpose of the Study:
- To prospectively compare foam- and gauze-based NPWT systems.
- Evaluate differences in wound healing, pain, cost, and hospital length of stay.
- Assess nurse-reported ease of use and time for dressing changes.
Main Methods:
- A randomized, controlled clinical trial was conducted.
- Eleven adult male subjects received either foam-based or gauze-based NPWT.
- Wound healing, pain, cost, and nurse perceptions were measured and analyzed using Wilcoxon rank sum tests.
Main Results:
- No statistically significant differences were found in median wound healing rates (length, width, depth) between foam and gauze NPWT systems.
- Pain ratings, wound care costs, and hospital length of stay did not differ significantly between the two systems.
- Nurses reported no significant differences in ease of use or time required for dressing changes.
Conclusions:
- This pilot study found no significant differences in effectiveness between foam- and gauze-based NPWT systems regarding wound healing, pain, cost, or hospital stay.
- Nursing experiences with ease of use and time for dressing changes were also comparable.
- Further research is recommended to confirm these findings and explore potential nuances in patient outcomes and nurse satisfaction.
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