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Updated: May 22, 2026

Preparation of Agar Bead Embedded Mycobacterium abscessus to Inoculate Immunocompetent Mice Intratracheally

Preparation of Agar Bead Embedded Mycobacterium abscessus to Inoculate Immunocompetent Mice Intratracheally

Published on: April 25, 2025

Brain abscess due to Wolinella recta and Streptococcus intermedius.

T J Marrie¹, E Kerr

¹Departments of Medicine, and Microbiology, Dalhousic University and the Victoria General Hospital, Halifax, Nova Scotia.

The Canadian Journal of Infectious Diseases = Journal Canadien Des Maladies Infectieuses

|May 4, 2012

Summary

This study reports a rare frontal lobe brain abscess caused by Wolinella recta and penicillin-resistant Streptococcus intermedius. Successful treatment involved prolonged antibiotic therapy and aspiration.

Keywords:

Brain abscess Streptococcus Wolinella

Related Experiment Videos

Last Updated: May 22, 2026

Preparation of Agar Bead Embedded Mycobacterium abscessus to Inoculate Immunocompetent Mice Intratracheally

Preparation of Agar Bead Embedded Mycobacterium abscessus to Inoculate Immunocompetent Mice Intratracheally

Published on: April 25, 2025

Area of Science:

Neurology
Infectious Diseases
Microbiology

Background:

Brain abscesses are serious intracranial infections requiring prompt diagnosis and treatment.
Wolinella recta is a rare pathogen in human infections, particularly in the central nervous system.
Streptococcus intermedius is a known cause of brain abscesses, with emerging antibiotic resistance.

Observation:

A 62-year-old female presented with a frontal lobe brain abscess.
The abscess was polymicrobial, involving Wolinella recta and two strains of Streptococcus intermedius.
One isolated strain of Streptococcus intermedius exhibited resistance to penicillin.

Findings:

Wolinella recta has not been previously reported as an etiology of brain abscess.
The patient required 60 days of antibiotic treatment and four aspirations for abscess resolution.
The source of the infection remained undetermined.

Implications:

This case highlights the importance of considering unusual pathogens like Wolinella recta in brain abscesses.
The presence of antibiotic-resistant Streptococcus intermedius underscores the need for susceptibility testing in treating such infections.
Extended treatment courses may be necessary for complex or polymicrobial brain abscesses.