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Toxicity of semecarpus anacardium extract
B Patwardhan1, M N Saraf, S B David
1Eisen Pharma Co. P. Ltd, 34/7 Erandwana, Pune 411 004, India.
Abstract:
Toxicity by oral route administration of S. anacardium extract with peanut oil was compared against the same extract emulsified with Tween-80 saline. The traditional way of administration with peanut oil was found to be safe and upto 25 mg/kg/day x9 days, increase in weight, RBCs & haemoglobin % was observed without mortality. Same dose with Tween-80 saline was found to have adverse effects regarding all the pharameters with 16.5% mortality. This study support Ayurvedic method of administration for efficacy without toxicity.
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