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Related Experiment Video

Updated: May 22, 2026

Social Threat-Safety Test Uncovers Psychosocial Stress-Related Phenotypes

Social Threat-Safety Test Uncovers Psychosocial Stress-Related Phenotypes

Published on: December 15, 2023

Resilience as a dynamic concept.

Michael Rutter¹

¹MRC Social Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, King’s College London, Denmark Hill, London SE5 8AF, UK. michael.rutter@kcl.ac.uk

Development and Psychopathology

|May 8, 2012

Summary

This summary is machine-generated.

Resilience varies greatly among individuals facing adversity. Some people show better outcomes due to "steeling effects" from prior stress, influencing future responses.

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Last Updated: May 22, 2026

Social Threat-Safety Test Uncovers Psychosocial Stress-Related Phenotypes

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Published on: December 15, 2023

Mindfulness in Motion (MIM): An Onsite Mindfulness Based Intervention (MBI) for Chronically High Stress Work Environments to Increase Resiliency and Work Engagement

Mindfulness in Motion (MIM): An Onsite Mindfulness Based Intervention (MBI) for Chronically High Stress Work Environments to Increase Resiliency and Work Engagement

Published on: July 1, 2015

Area of Science:

Psychology
Behavioral Science
Genetics

Background:

Individual responses to environmental adversity exhibit significant heterogeneity.
Resilience is inferred when individuals demonstrate better outcomes despite comparable adversity exposure.
Adverse experiences can sensitize or strengthen individuals for future stress, known as 'steeling effects'.

Purpose of the Study:

To review findings on 'steeling effects' in animal models and humans.
To examine gene-environment interactions influencing resilience.
To explore life course effects and turning points that foster resilience.

Main Methods:

Review of existing literature on resilience and 'steeling effects'.
Analysis of 'natural experiments' to understand environmental mediation of risk.
Examination of gene-environment interaction studies and life course research.

Main Results:

Evidence supports 'steeling effects' in both animal models and humans.
Genetic influences may affect responsivity to all environments, not solely adverse ones.
Life course turning points can enhance coping and foster resilience.

Conclusions:

Resilience is influenced by a complex interplay of environmental, genetic, and life course factors.
Understanding these factors is crucial for developing interventions to foster resilience.
Further research into gene-environment interactions and life course effects is warranted.