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Chemotherapy in metastatic nonanaplastic thyroid cancer: experience at the Institut Gustave-Roussy
J P Droz1, M Schlumberger, P Rougier
1Department of Medicine, Institut Gustave-Roussy, Villejuif, France.
Tumori
|October 31, 1990
Abstract:
Forty-nine patients with metastatic nonanaplastic thyroid carcinoma were treated over a 10-year period. Five successive chemotherapeutic protocols were used: a combination of doxorubicin, etoposide, 5-fluorouracil and cyclophosphamide; elliptinium acetate; doxorubicin; cisplatin; and the combination of doxorubicin and cisplatin. Results obtained with the different protocols were very disappointing, with only two objective responses (3%). Phase II trials with new chemotherapeutic agents are warranted in selected cases of nonanaplastic metastatic thyroid carcinoma.