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Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies
Published on: January 3, 2011
Confocal microscopy of central toxic keratopathy
Ivey L Thornton1, Gary N Foulks, Richard A Eiferman
1Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, KY, USA.
Purpose:
To examine the confocal microscopic findings in a case of late-onset central toxic keratopathy.
Methods:
A 46-year-old man with central toxic keratopathy 2 months after IntraLASIK underwent confocal microscopy to examine the cellular findings within the flap interface.
Results:
The confocal microscopy in central toxic keratopathy reveals activated keratocytes without aggregation of inflammatory cells.
Conclusions:
The lack of inflammatory cells in the interface is consistent with the noninflammatory nature of central toxic keratopathy. To our knowledge, this is the first report of confocal microscopy in presumed central toxic keratopathy.
