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Updated: May 22, 2026

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
Published on: June 13, 2025
Practical approach to endoscopic management for bleeding gastric varices
1Department of Gastroenterology, Liver Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, Korea. limys@amc.seoul.kr
Gastric varices bleeding is severe. This review covers classification, pathophysiology, and endoscopic/radiological treatments, focusing on N-butyl-2-cyanoacrylate for variceal obturation.
Area of Science:
- Gastroenterology
- Interventional Radiology
Background:
- Gastric varices present a severe bleeding risk, though less common than esophageal varices.
- Therapeutic options for gastric varices have expanded with new endoscopic and interventional radiological techniques.
Purpose of the Study:
- To review the classification and pathophysiology of gastric varices.
- To introduce current endoscopic and interventional radiological management strategies.
- To detail the practical application of endoscopic variceal obturation using N-butyl-2-cyanoacrylate.
Main Methods:
- Literature review of gastric variceal management.
- Overview of endoscopic and interventional radiological procedures.
- Detailed description of endoscopic variceal obturation technique.
Main Results:
- Gastric varices require specific management due to their severity.
- Endoscopic and interventional radiology offer effective treatment modalities.
- N-butyl-2-cyanoacrylate is a key agent for endoscopic variceal obturation.
Conclusions:
- Effective management of gastric varices involves understanding their pathophysiology and available treatments.
- Endoscopic variceal obturation with N-butyl-2-cyanoacrylate is a viable and practical therapeutic option.
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