Related Experiment Video
Updated: May 22, 2026

Aortic Ring Assay
Published on: November 24, 2009
Clinical course of vascular rings and risk factors associated with mortality
Yoon Jung Suh1, Gi Beom Kim, Bo Sang Kwon
1Department of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.
Insights
Vascular rings, anomalies of great arteries, can cause serious health issues. Complex heart disease is a significant risk factor for mortality in these patients, highlighting the need for early diagnosis and intervention.
Area of Science:
- Cardiology
- Pediatric Surgery
- Medical Imaging
Background:
- Vascular rings are congenital anomalies of the great arteries.
- These anomalies can lead to significant respiratory and feeding difficulties in infants and children.
- Understanding risk factors for mortality is crucial for managing these patients.
Purpose of the Study:
- To analyze a cohort of patients diagnosed with vascular rings.
- To identify and evaluate risk factors associated with mortality in patients with vascular rings.
Main Methods:
- Retrospective review of patients diagnosed with vascular rings between 1997 and 2010.
- Diagnostic confirmation using cardiac computed tomography (CT) or magnetic resonance imaging (MRI).
Main Results:
- Thirty-five patients with vascular rings were identified, with a median diagnosis age of 7 months.
- Common types included double aortic arch, right aortic arch with persistent left ligamentum arteriosum, aberrant subclavian artery, and pulmonary sling.
- Fifteen patients had associated cardiovascular anomalies, and twenty underwent surgery; mortality was significantly linked to complex heart disease (p=0.002).
Conclusions:
- Vascular rings encompass diverse anomalies with varying prognoses.
- Complex heart disease is a significant predictor of mortality in vascular ring patients.
- Prompt diagnosis and surgical intervention are vital for symptomatic individuals.
Background And Objectives:
Vascular rings refer to anomalies of the great arteries that cause respiratory or feeding problems. The purpose of this study was to analyze a series of patients with vascular rings and evaluate associated risk factors for mortality.
Subjects And Methods:
A retrospective review of all patients identified with vascular rings between 1997 and 2010 in the Seoul National University Children's Hospital.
Results:
Thirty-five patients were diagnosed with vascular rings (median age at diagnosis, 7 months). The vascular rings of 32 patients were confirmed by cardiac computed tomography or magnetic resonance imaging. The types of vascular rings were: a double aortic arch in ten patients, a right aortic arch with persistent left ligamentum arteriosum in seven, an aberrant subclavian artery in seven, a pulmonary sling in eight, and others types in three patients. Eleven patients were asymptomatic. Gastrointestinal and respiratory symptoms were seen in ten and sixteen patients, respectively. Associated cardiovascular anomalies were present in fifteen patients. Twenty patients with definite symptoms underwent surgical treatment. The median interval between diagnosis and operation was 6 days. Four patients eventually died; three deaths were associated with complex heart diseases, and one had pulmonary artery sling with severe tracheal stenosis. Only the presence of a complex heart disease significantly influenced mortality (p=0.002).
Conclusion:
Vascular rings include several types of anomalies, each with a different prognosis and symptoms. The presence of a complex heart disease was significantly associated with mortality. Early diagnosis and timely surgery in symptomatic patients are essential.
Related Concept Videos
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Aneurysm III: Interprofessional Care
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
Aortic Regurgitation I: Introduction
Vascular Resistance
The primary determinants of vascular resistance are vessel diameter, blood viscosity, and vessel length. Among these, vessel diameter plays the most significant role due to the fourth power relationship described by...
Endocarditis II: Clinical Features of Infective Endocarditis
