Risk factors for delayed recanalization of calf vein thrombosis

Yang Jin Park1, Kyung-Bok Lee, Dong-Ik Kim

  • 1Division of Vascular Surgery, Department of Surgery, Cardiac and Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Insights

Oral anticoagulation therapy significantly improves recanalization rates in calf vein thrombosis (CVT). Immobilization and malignancy are key risk factors for delayed recanalization in CVT patients.

Area of Science:

  • Vascular Medicine
  • Thrombosis Research
  • Medical Diagnostics

Background:

  • Isolated calf vein thrombosis (CVT) is a common vascular condition.
  • Understanding risk factors for delayed recanalization is crucial for effective patient management.

Purpose of the Study:

  • To identify risk factors associated with delayed recanalization in patients diagnosed with isolated calf vein thrombosis (CVT).

Main Methods:

  • A cohort of 110 patients with CVT was studied using ultrasonography for diagnosis and follow-up.
  • Recanalization rates were assessed at 1 and 3 months post-diagnosis.
  • Statistical analysis was performed to identify independent risk factors for delayed recanalization.

Main Results:

  • Oral anticoagulation therapy was associated with significantly higher recanalization rates (84% vs. 65%).
  • Malignancy (OR, 2.789) and immobilization (OR, 4.191) were identified as independent risk factors for delayed recanalization.
  • Oral anticoagulation was an independent factor promoting recanalization (OR, 0.300).

Conclusions:

  • Patients with isolated CVT treated without oral anticoagulation experienced higher rates of delayed recanalization.
  • Immobilization and malignancy are significant independent risk factors contributing to delayed CVT recanalization.
Abstract

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