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[Atractylis gummifera: from poisoning to the analytic methods]
Samir Ahid1, Mina Ait El Cadi, Bouchra Meddah
1Laboratoire de pharmacologie-toxicologie, Université Mohammed V Souissi, Rabat, Maroc.
Atractylis gummifera plant poisoning causes severe health issues. Detecting atractyloside and carboxyatractyloside in biological fluids is crucial for diagnosis and treatment.
Area of Science:
- Toxicology
- Plant Chemistry
- Analytical Chemistry
Context:
- Atractylis gummifera causes severe, often fatal, poisonings annually.
- Morocco reported 153 cases between 1980 and 1995.
- Clinical diagnosis is challenging due to rapid progression and frequency of poisonings.
Purpose:
- To describe Atractylis gummifera poisoning.
- To review toxicological analysis methods for detecting key toxins.
- To highlight the importance of analytical methods in managing plant-induced poisonings.
Summary:
- Atractylis gummifera poisoning presents diagnostic challenges for clinicians.
- Detection of atractyloside and carboxyatractyloside in biological samples is essential.
- This review covers analytical techniques from colorimetric assays to modern chromatographic methods.
Impact:
- Improved diagnostic accuracy for Atractylis gummifera poisoning.
- Facilitates timely and effective clinical management of patients.
- Provides a comprehensive overview of analytical methodologies for toxicological screening.
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