Related Experiment Video
Updated: May 22, 2026
A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
Percutaneously placed central venous catheter-related sepsis in Canadian neonatal intensive care units
Jonathan Wong1, Kimberly Dow, Prakesh S Shah
1Department of Pediatrics, Kingston General Hospital, Kingston, Ontario, Canada.
Objectives:
To estimate daily risk, variability between centers, and impact on outcomes of catheter-related sepsis (CRS) among preterm neonates.
Study Design:
Retrospective evaluation of data from centers in the Canadian Neonatal Network for neonates born at <29 weeks or <1000 g who had a percutaneously placed central venous catheter (PCVC) in place for ≥ 48 hours.
Results:
Of 2966 infants with a PCVC, 582 (19.6%) developed CRS (overall rate 11/1000 catheter days). The daily risk of CRS varied between 1% and 2% in the first 28 days, and rates of CRS varied between centers (0 to 37 infections/1000 catheter days). Birth weight and gestational age were lower, and Score for Neonatal Acute Physiology and day of life of insertion were higher among those with CRS. Average length of stay was 6.2 days longer for those with CRS. There was no difference in mortality or major morbidities between infants who had CRS and those without CRS.
Conclusions:
No threshold length of catheter usage days within the first 28 days was identified at or after which the risk of CRS increased. Marked variability between centers was present. Patients with CRS had an increased length of stay, but no increased risk for mortality or major morbidities.
Related Concept Videos
01:27Parentral Nutrition: Centeral and Peripheral Parental Nutrition
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
01:22Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
01:26Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
01:29Endocarditis IV: Nursing Management
01:25Endocarditis I: Introduction
01:28Cardiac Catheterization I: Pre-Procedure Overview