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Updated: May 22, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Obesity--does it occur in Nigerian children with sickle cell anemia
Samuel Olufemi Akodu1, Ijeoma Nnenna Diaku-Akinwumi, Olisamedua Fidelis Njokanma
1Department of Paediatrics, Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria. femiakodu@hotmail.com
Insights
Obesity is present in children with sickle cell anemia in Lagos, Nigeria, affecting 2.5% of those with hemoglobin genotype SS. Public health initiatives should include these vulnerable children in obesity prevention programs.
Area of Science:
- Pediatrics
- Public Health
- Genetics
Background:
- Children with sickle cell anemia (SCA) often experience growth deficits, making obesity seem unlikely.
- Understanding the prevalence of obesity in SCA populations is crucial for comprehensive health management.
Purpose of the Study:
- To determine the prevalence of obesity among children with sickle cell anemia in Lagos, Nigeria.
- To compare obesity rates between children with SCA and healthy controls.
Main Methods:
- A random sample of children aged 2-15 years with SCA and healthy controls (hemoglobin genotype AA) were recruited.
- Anthropometric measurements (weight, height) were taken to calculate Body Mass Index (BMI).
- Obesity was defined using World Health Organization (WHO) standard criteria for BMI and weight-for-height-for-age.
Main Results:
- The prevalence of obesity was 2.5% in children with SCA (hemoglobin genotype SS) and 3.8% in controls (hemoglobin genotype AA).
- Obesity was most prevalent in younger children with SCA and adolescents among controls.
- All obese children with SCA were from upper socioeconomic strata.
Conclusions:
- Obesity is a reality among children with sickle cell anemia in Lagos.
- Public health strategies for obesity prevention and control must actively include children with SCA.
Abstract:
Children with sickle cell anemia are vulnerable to growth deficits; thus, it would be thought that obesity would be rare among them. The objective of the study is to examine the prevalence of obesity in a sickle cell anemia population in Lagos. A random sample of children with sickle cell anemia aged 2-15 years was interviewed and anthropometric measurements including weight and height were taken. Their body mass index (BMI) was calculated. Participants were classified as obese or not obese by their BMI or weight-for-height-for-age using World Health Organization standard definitions. The overall prevalence of obesity was 2.5% and 3.8% among hemoglobin genotype SS subjects and hemoglobin genotype AA controls, respectively. The age-specific prevalence for obesity was highest among the adolescent age category in hemoglobin genotype AA controls and the childhood age category in subjects with sickle cell anemia. All the obese subjects with sickle cell anemia were from upper socioeconomic strata, while two and one of the three subjects with hemoglobin genotype AA were from upper and middle socioeconomic strata, respectively. Obesity does exist among children with sickle cell anemia in Lagos, Nigeria. Public health programs aimed at prevention and control of obesity must include children with sickle cell anemia.
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