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Updated: May 22, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Behçet's disease in concurrence with psoriasis.

S Cho¹, S B Cho, M J Choi

¹Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.

Journal of the European Academy of Dermatology and Venereology : JEADV

|May 10, 2012

Summary

This study examined nine patients with both Behçet's disease (BD) and psoriasis, finding minimal to average psoriasis activity regardless of disease onset. The research suggests a potential interplay between these two chronic inflammatory conditions.

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Last Updated: May 22, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Area of Science:

Immunodermatology
Rheumatology
Systemic Inflammatory Diseases

Background:

Behçet's disease (BD) involves multisystemic vasculitis, while psoriasis is characterized by epidermal hyperplasia.
Both chronic inflammatory conditions share overlapping pathogenetic mechanisms.
Concurrent diagnoses of BD and psoriasis are infrequently reported in medical literature.

Purpose of the Study:

To investigate and document the clinical features of patients diagnosed with both Behçet's disease and psoriasis.
To analyze the interplay between these two distinct inflammatory conditions in affected individuals.

Main Methods:

A retrospective analysis was conducted on the medical records of nine patients with co-existing BD and psoriasis.
Data collected included patient demographics, clinical activity of both diseases, and treatment effects.
Evaluations were performed at the BD Specialty Clinic of Severance Hospital.

Main Results:

The study included nine patients (2 males, 7 females) with co-occurring BD and psoriasis vulgaris.
Seven patients (77.8%) presented with incomplete Behçet's disease.
In most cases, BD preceded psoriasis (55.6%), with active BD noted in these patients, while psoriasis activity remained minimal to average across all nine patients.

Conclusions:

This study provides insights into the clinical manifestations of nine patients with concurrent Behçet's disease and psoriasis.
While the precise pathogenesis remains elusive, findings suggest a potential bidirectional influence between BD and psoriasis.
Further research is warranted to elucidate the complex relationship between these conditions.