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Updated: May 22, 2026

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Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty
Published on: September 17, 2014
Refractive surgery after Descemet's stripping endothelial keratoplasty
1Department of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY 10467, USA.
Current Opinion in Ophthalmology
|May 10, 2012
Summary
Refractive surgeries like LASIK and PRK can correct vision problems after Descemet
Area of Science:
- Ophthalmology
- Corneal Surgery
- Refractive Surgery
Background:
- Descemet's Stripping Endothelial Keratoplasty (DSEK) is a common surgical procedure for endothelial dysfunction.
- Refractive errors are a significant cause of patient dissatisfaction following DSEK, even when the surgery is anatomically successful.
Purpose of the Study:
- To review secondary refractive surgical options for patients experiencing refractive errors after DSEK.
- To address patient dissatisfaction stemming from visual compromise post-DSEK.
Main Methods:
- Review of existing literature on refractive surgeries performed after DSEK.
- Analysis of various surgical techniques including cataract extraction, LASIK, PRK, and PTK.
Main Results:
- Cataract extraction with intraocular lens (IOL) implantation effectively restores vision in cases with lens opacities.
- Laser-Assisted In Situ Keratomileusis (LASIK) and Photorefractive Keratectomy (PRK) are suitable for correcting simple refractive errors.
- Phototherapeutic Keratectomy (PTK) can address visually significant subepithelial fibrosis and scarring.
Conclusions:
- Secondary refractive surgeries are often necessary for optimal visual rehabilitation after DSEK.
- Procedures like cataract extraction, LASIK, PRK, PTK, and combination therapies can enhance corneal clarity and visual acuity.
- Further research and technological advancements are needed to optimize the timing and outcomes of these secondary procedures.

