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Updated: May 22, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
Percutaneous coronary intervention in cardiogenic shock complicating acute ST-elevation myocardial infarction-a
Vijayakumar Subban1, Anand Gnanaraj, Balashankar Gomathi
1Department of Cardiology, Madras Medical Mission, Tamilnadu, India.
Insights
Early revascularization improves survival in acute myocardial infarction (AMI) with cardiogenic shock (CS). Achieving TIMI 3 flow in the infarct-related artery is key for survival after percutaneous coronary intervention (PCI).
Area of Science:
- Cardiology
- Interventional Cardiology
Background:
- Mortality in acute myocardial infarction (AMI) with cardiogenic shock (CS) remains high (70-80%) despite pharmacological treatments.
- Early revascularization is crucial for improving survival in AMI patients experiencing CS.
Purpose of the Study:
- To assess predictors of mid-term outcomes in ST-segment elevation myocardial infarction (STEMI) patients with CS.
- Evaluate survival rates after percutaneous coronary intervention (PCI) in STEMI with CS.
Main Methods:
- Analysis of 41 patients undergoing primary or rescue PCI for CS.
- Comparison of baseline, angiographic, and PCI data with 30-day and 1-year survival.
Main Results:
- Higher rates of transfer admissions and cardiopulmonary resuscitations were observed in non-survivors.
- Pre-procedure Thrombolysis In Myocardial Infarction (TIMI) flow grade 3 in the infarct-related artery (IRA) significantly correlated with better survival (P=0.0005).
- Successful PCI was achieved in 48.8% of patients, with significantly better short-term survival compared to failed PCI (80% vs 9.6%). 30-day mortality was 56.1%.
Conclusions:
- Mortality remains high in STEMI with CS, even after PCI.
- Achieving IRA patency with TIMI 3 flow is the primary determinant of survival.
- Patients discharged from the hospital after PCI demonstrate good survival and functional status.
Background:
Mortality in acute myocardial infarction (AMI) complicated by cardiogenic shock (CS) approaches 70 - 80%, regardless of the type of pharmacological treatment. Early revascularisation improves survival in AMI with CS. Our aim is to assess the predictors of mid-term outcome after percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) and CS.
Methods:
Forty-one patients who underwent primary or rescue PCI for CS were analysed comparing their baseline, angiographic, PCI data, 30-day and 1-year survival.
Results:
There were no significant differences between survivors and non-survivors in baseline characters, except for more number of transfer admissions (P= 0.0005), and cardiopulmonary resuscitations (P= 0.015) in the later group. The mean time between myocardial infarction (MI) onset to shock and MI onset to revascularisation were 12.8 ± 12.9 hours and 17.0 ± 16.8 hours, respectively. Patients with better pre-procedure thrombolysis in myocardial infarction (TIMI) flow in the infarct-related artery (IRA) had better survival (P= 0.0005). Successful PCI was achieved in 48.8% of patients. The 30-day mortality was 56.1% and all were prior to hospital discharge. Patients with successful PCI had better short-term survival in comparison with patients with failed PCI (80% vs 9.6%). Eighteen patients who survived at 30 days were followed up for 12-72 months (mean 28.5 ± 5.4 months). Fifteen patients survived at 1 year after PCI and all were in good functional status.
Conclusion:
Mortality remains high even with PCI. Achieving IRA patency with TIMI 3 flow is the main determinant of survival. Survival and functional status are good in patients who are discharged from hospital.
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