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Primary dural lymphoma masquerading as a meningioma
Kaushal M Kulkarni1, Linda Sternau, Sander R Dubovy
1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA. kaushal.kulkarni@gmail.com
Summary
A rare case of primary dural B-cell lymphoma mimicked a meningioma, causing vision loss. Prompt diagnosis and treatment are crucial for preserving sight in such conditions.
Area of Science:
- Neuro-oncology
- Ophthalmology
- Pathology
Background:
- Primary dural lymphomas are rare tumors that can present insidiously.
- These tumors can mimic more common intracranial masses, leading to diagnostic challenges.
Observation:
- A 39-year-old woman presented with progressive blurred vision and optic nerve abnormalities.
- Initial imaging suggested an en plaque meningioma compressing the optic nerve.
Findings:
- Surgical debulking and subsequent histopathologic analysis revealed a low-grade B-cell lymphoma, not a meningioma.
- Extensive workup confirmed no systemic involvement, indicating a primary dural origin.
Implications:
- This case highlights the importance of considering lymphoma in the differential diagnosis of optic nerve compression, even when meningioma is suspected.
- Accurate histopathologic and molecular analysis is essential for correct diagnosis and appropriate management of primary dural tumors.
- Early recognition and treatment of primary dural lymphomas can prevent irreversible vision loss and systemic complications.
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