Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optically programable quasi phase matching in four-wave mixing.

Nature communications·2025
Same author

All-optical Stern-Gerlach effect in the time domain.

Optics express·2024
Same author

Toward multimode-fiber shape sensing.

Optics letters·2023
Same author

Ultrahigh scan-rate quasi-distributed acoustic sensing system using array match interrogation.

Optics express·2022
Same author

Two-wavelength phase-sensitive OTDR sensor using perfect periodic correlation codes for measurement range enhancement, noise reduction and fading compensation.

Optics express·2021
Same author

Visual data detection through side-scattering in a multimode optical fiber.

Optics letters·2020
Same journal

Generalizable framework for multi-site bone density prediction using non-dominant wrist optical biomarkers.

Biomedical optics express·2026
Same journal

Erratum: Review of dynamic optical coherence tomography for intracellular motility [Invited]: errata.

Biomedical optics express·2026
Same journal

Digital-micromirror-device-based illumination strategies for background suppression in single-molecule localization microscopy.

Biomedical optics express·2026
Same journal

Synergistic combination of convective self-assembly and hollow core fiber for sensitive SERS detection of glucose molecules.

Biomedical optics express·2026
Same journal

Multimodal diagnostic network integrating infrared and mass spectra for lung cancer.

Biomedical optics express·2026
Same journal

Multimodal Optical Biosensing for Precision Medicine and Healthcare: Introduction to the feature issue.

Biomedical optics express·2026
See all related articles

Related Experiment Video

Updated: May 22, 2026

Ovarian Cancer Detection Using Photoacoustic Flow Cytometry
09:18

Ovarian Cancer Detection Using Photoacoustic Flow Cytometry

Published on: January 17, 2020

Photoacoustic thermal diffusion flowmetry.

Adi Sheinfeld1, Avishay Eyal

  • 1School of Electrical Engineering, Faculty of Engineering, Tel-Aviv University, Ramat Aviv, Tel-Aviv, Israel.

Biomedical Optics Express
|May 11, 2012
PubMed
Summary
This summary is machine-generated.

This study introduces a novel photothermal-photoacoustic technique for Thermal Diffusion Flowmetry (TDF) to measure blood flow. The method accurately estimated blood velocity in phantom vessels, paving the way for simultaneous blood flow and oxygen saturation measurements.

Keywords:
(170.4090) Modulation techniques(170.5120) Photoacoustic imaging(300.6260) Spectroscopy, diode lasers(300.6430) Spectroscopy, photothermal

More Related Videos

Three-dimensional Optical-resolution Photoacoustic Microscopy
08:31

Three-dimensional Optical-resolution Photoacoustic Microscopy

Published on: May 3, 2011

Detection and Isolation of Circulating Melanoma Cells using Photoacoustic Flowmetry
09:52

Detection and Isolation of Circulating Melanoma Cells using Photoacoustic Flowmetry

Published on: November 25, 2011

Related Experiment Videos

Last Updated: May 22, 2026

Ovarian Cancer Detection Using Photoacoustic Flow Cytometry
09:18

Ovarian Cancer Detection Using Photoacoustic Flow Cytometry

Published on: January 17, 2020

Three-dimensional Optical-resolution Photoacoustic Microscopy
08:31

Three-dimensional Optical-resolution Photoacoustic Microscopy

Published on: May 3, 2011

Detection and Isolation of Circulating Melanoma Cells using Photoacoustic Flowmetry
09:52

Detection and Isolation of Circulating Melanoma Cells using Photoacoustic Flowmetry

Published on: November 25, 2011

Area of Science:

  • Biomedical Optics
  • Physiological Measurement
  • Thermal Physics

Background:

  • Thermal Diffusion Flowmetry (TDF) is a established method for assessing tissue perfusion.
  • Conventional TDF relies on inducing and measuring temperature changes to calculate blood flow.
  • Existing methods can be invasive or lack the precision for complex physiological monitoring.

Purpose of the Study:

  • To develop and validate a new photothermal-photoacoustic (PT-PA) approach for TDF.
  • To investigate the theoretical and experimental feasibility of PT-PA TDF.
  • To explore the potential for simultaneous blood flow and oxygen saturation measurements.

Main Methods:

  • Utilized photothermal (PT) heat deposition and photoacoustic (PA) thermometry for TDF implementation.
  • Employed directly modulated 830 nm laser diodes for both PT and PA excitation.
  • Delivered excitation beams via a single optical fiber to the target tissue.
  • Validated the method using a blood-filled phantom vessel and compared results with theoretical models.

Main Results:

  • Experimental data from the phantom vessel aligned with theoretical predictions.
  • A simplified lumped thermal model accurately fitted the experimental data.
  • Estimated blood velocity values were obtained for various flow rates.
  • Demonstrated the potential for non-invasive measurements using a single fiber probe.

Conclusions:

  • The novel PT-PA TDF method is theoretically sound and experimentally viable for measuring blood flow.
  • The technique offers a promising platform for advanced physiological monitoring.
  • Future integration of multiple wavelengths could enable simultaneous assessment of blood flow and oxygen saturation.