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Updated: May 22, 2026

Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
Published on: June 13, 2022
Anilides and toluidides of 3beta-acetyloleanolic acid
1Department of Organic Chemistry, Poznan University of Medical Sciences, Grunwaldzka Str. 6, 60 - 780 Poznan, Poland. bcwynar@ump.edu.pl
Abstract:
Amide formation is one of the reactions that can be undertaken within the carboxyl group of oleanolic acid. A simple method for oleanolic acid anilide and toluidides synthesis is presented. The influence of the location of the methyl substituent on the reactivity of the amine group was tested and the "ortho effect" of the methyl substituent within the molecule of o-toluidine on the time of reaction was observed. The structures of the newly obtained compounds were determined by spectroscopic methods.
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