[Recurrence of idiopathic membranous glomerulopathy]

In 30 patients with idiopathic membranous glomerulopathy during prednisone treatment and prednisone and cyclophosphamide treatment resp. partial or complete clinical remission was recorded. In the course of the investigation (118 +/- 77 months) in 7 patients 1-4 relapses occurred. The relapses occurred more frequently in women. There was no difference between the two groups as regards clinical manifestations and morphological findings at the onset of the disease. All relapses were treated in the same way as the first attack. Treatment had in all patients the same result as during the first attack and in the course of the investigation in none of the patients deterioration of renal functions was recorded. In case of effective immunosuppressive treatment the prognosis of patients with relapses is not worse than in patients without relapses.