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Sigpep: calculating unique peptide signature transition sets in a complete proteome background

Kenny Helsens1, Michael Mueller, Niels Hulstaert

  • 1Department of Medical Protein Research, VIB, Ghent, Belgium.

Proteomics
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PubMed

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Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...