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High-throughput Screening for Small-molecule Modulators of Inward Rectifier Potassium Channels
Published on: January 27, 2013
Fluoride triggered fluorescence "turn on" sensor for Zn2+ ions based on pentaquinone scaffold that works as a
Vandana Bhalla1, Roopa, Manoj Kumar
1Department of Chemistry, UGC Sponsored-Centre for Advanced Studies-I, Guru Nanak Dev University, Amritsar-143005, Punjab, India. vanmanan@yahoo.co.in
Organic Letters
|May 15, 2012
Abstract:
A pentaquinone based compound 3a has been synthesized which exhibits pronounced fluorescence enhancement in the presence of Zn(2+) ions under a F(-) triggered synergistic effect. Derivative 3a also behaves as a molecular keypad lock with sequential chemical inputs of Zn(2+) and F(-) ions.
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