[Comparative biological testing of Ketac-Bond glass ionomer cement]

The biocompatibility of a fast setting glass-ionomer cement and of reference materials (zink-phosphate cement, silicate cement, ZOE, composite) was assessed in a comparative biological study. Cytotoxicity testing revealed 90% counted cell numbers after incubation for 96 hours. Subcutaneous implantation tests resulted in slight, moderate and severe connective tissue reactions. In contrast to these results the three different usage tests revealed slight, reversible pulp reactions in rat incisors, pig and human teeth. After 90 days of testing there was no chronic persistent pulp irritation. It may be concluded that Ketac-Bond, is an acceptable restorative material.