Prolonged stay in intensive care unit is a powerful predictor of adverse outcomes after cardiac operations

Balakrishnan Mahesh1, Cliff K Choong, Kimberley Goldsmith

  • 1Department of Cardiothoracic Surgery, Papworth Hospital, Cambridgeshire, United Kingdom. drbmahesh@yahoo.co.uk

Insights

Prolonged intensive care unit (ICU) stays significantly increase in-hospital mortality and reduce long-term survival rates after surgery. This highlights the critical impact of extended ICU duration on patient outcomes.

Area of Science:

  • Critical Care Medicine
  • Surgical Outcomes Research
  • Patient Prognosis

Background:

  • Understanding the implications of extended intensive care unit (ICU) stays is crucial for surgical patient management.
  • Previous research has indicated potential negative associations between prolonged ICU duration and patient outcomes.

Purpose of the Study:

  • To investigate the impact of prolonged intensive care unit (ICU) stay on in-hospital mortality and long-term survival following surgical procedures.
  • To identify prolonged ICU stay as a predictor of adverse outcomes.

Main Methods:

  • Analysis of prospectively collected data from 6,101 surgical patients (2003-2007).
  • Definition of prolonged ICU stay as ≥3 days postoperatively, with <3 days as controls.
  • Utilized univariate and multiple variable analyses to identify risk factors and predictors.

Main Results:

  • 18.7% of patients experienced prolonged ICU stays, showing significantly higher ICU and hospital mortality rates compared to controls.
  • Patients with prolonged ICU stays had substantially lower 1-year and 3-year survival rates post-discharge.
  • Prolonged ICU stay was identified as an independent predictor of prolonged hospital stay, increased mortality, and poorer long-term survival.

Conclusions:

  • Prolonged intensive care unit (ICU) stay is a significant predictor of adverse outcomes.
  • This includes immediate, short-term, and long-term negative impacts on patients undergoing cardiac operations.
  • The findings underscore the importance of minimizing prolonged ICU stays to improve surgical patient prognosis.
Abstract

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