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Published on: January 16, 2019
Prolonged stay in intensive care unit is a powerful predictor of adverse outcomes after cardiac operations
Balakrishnan Mahesh1, Cliff K Choong, Kimberley Goldsmith
1Department of Cardiothoracic Surgery, Papworth Hospital, Cambridgeshire, United Kingdom. drbmahesh@yahoo.co.uk
Insights
Prolonged intensive care unit (ICU) stays significantly increase in-hospital mortality and reduce long-term survival rates after surgery. This highlights the critical impact of extended ICU duration on patient outcomes.
Area of Science:
- Critical Care Medicine
- Surgical Outcomes Research
- Patient Prognosis
Background:
- Understanding the implications of extended intensive care unit (ICU) stays is crucial for surgical patient management.
- Previous research has indicated potential negative associations between prolonged ICU duration and patient outcomes.
Purpose of the Study:
- To investigate the impact of prolonged intensive care unit (ICU) stay on in-hospital mortality and long-term survival following surgical procedures.
- To identify prolonged ICU stay as a predictor of adverse outcomes.
Main Methods:
- Analysis of prospectively collected data from 6,101 surgical patients (2003-2007).
- Definition of prolonged ICU stay as ≥3 days postoperatively, with <3 days as controls.
- Utilized univariate and multiple variable analyses to identify risk factors and predictors.
Main Results:
- 18.7% of patients experienced prolonged ICU stays, showing significantly higher ICU and hospital mortality rates compared to controls.
- Patients with prolonged ICU stays had substantially lower 1-year and 3-year survival rates post-discharge.
- Prolonged ICU stay was identified as an independent predictor of prolonged hospital stay, increased mortality, and poorer long-term survival.
Conclusions:
- Prolonged intensive care unit (ICU) stay is a significant predictor of adverse outcomes.
- This includes immediate, short-term, and long-term negative impacts on patients undergoing cardiac operations.
- The findings underscore the importance of minimizing prolonged ICU stays to improve surgical patient prognosis.
Background:
The aim of this study was to examine the impact of prolonged intensive care unit (ICU) stay on in-hospital mortality and long-term survival.
Methods:
Prospectively collected data from 6,101 consecutive patients who underwent surgery between 2003 and 2007 were analyzed. Prolonged ICU stay was defined as a total duration of ICU stay of 3 days or more postoperatively, including readmissions; patients with an ICU stay less than 3 days were identified as controls. Univariate and multiple variable analyses were performed to identify risk factors associated with prolonged ICU stay.
Results:
Of 6,101 patients, 1,139 (18.7%) patients had a prolonged ICU stay. These patients had a higher ICU mortality (10%) compared with controls (0.6%; p < 0.001). On discharge from the ICU, their hospital mortality was still 6-fold higher (1.2%) compared with controls (0.2%; p < 0.001). Finally, the patients who had prolonged ICU stays had lower survival after discharge from the ICU-89.2% and 81.2% at 1 year and 3 years, respectively, compared with 97.8% and 93.6%, respectively, for controls (p < 0.001). Multiple variable analysis revealed prolonged ICU stay to be an independent predictor of prolonged hospital stay, higher hospital mortality, and poorer long-term survival (all p < 0.001).
Conclusions:
Prolonged ICU stay is an important predictor of adverse immediate, short-term, and long-term outcomes after cardiac operations.
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Endotracheal Tube Extubation
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals.