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Published on: February 10, 2020
Tramadol-induced seizures and trauma
H Farajidana1, H Hassanian-Moghaddam, N Zamani
1Department of Forensic Medicine and Toxicology, Tehran University of Medical Sciences, Hazrat Rasoul Akram Hospital, Tehran, Iran.
Summary
Tramadol-induced seizures can cause injuries, with facial trauma being most common. Serious head injuries occurred in about 1% of patients experiencing tramadol seizures.
Area of Science:
- Medical Toxicology
- Neurology
- Emergency Medicine
Background:
- Tramadol is a widely used analgesic with a known risk of seizures, particularly with overdose.
- Seizures can lead to physical trauma, necessitating an understanding of injury patterns.
Purpose of the Study:
- To investigate the prevalence, types, and locations of injuries resulting from tramadol-induced seizures.
- To identify risk factors and patterns of trauma associated with tramadol-related seizures.
Main Methods:
- A retrospective study included 232 patients presenting with tramadol-induced seizures over a 14-month period.
- Data collected included demographics, tramadol dosage, seizure characteristics, and injury details (type and site).
Main Results:
- Trauma occurred in 24.6% of patients, with facial injuries being the most frequent (9.5%).
- Head injuries, though less common, were noted as the only serious injury, affecting approximately 1% of patients.
- No significant differences in age, gender, dose, or seizure frequency were found between patients with and without trauma.
Conclusions:
- Facial trauma is the most common injury associated with tramadol-induced seizures.
- Head injury is the most serious injury, though infrequent, highlighting the need for vigilance.
- Understanding injury patterns aids in managing patients with tramadol-induced seizures.
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