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Published on: August 16, 2018
A new sesquiterpene lactone from Elephantopus tomentosus
Bei Wang1, Wen-Li Mei, Yan-Bo Zeng
1Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101, China.
Abstract:
A new sesquiterpene lactone, named tomenphantopin H (1), together with two known germacranolides, 2β-methoxy-2-deethoxy-8-O-deacylphantomolin-8-O-tiglinate (2) and 2-deethoxy-2-hydroxyphantomolin (3), was isolated from the whole plant of Elephantopus tomentosus Linn. The new compound was completely elucidated using a combination of 1D and 2D NMR techniques (COSY, HMQC, and HMBC) and HR-ESI-MS analyses. All compounds exhibited antibacterial activity.