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Guidelines adherence and hypertension control at a tertiary hospital in Malaysia
Nafees Ahmad1, Yahaya Hassan, Balamurugan Tangiisuran
1Researcher Lecturer, Department of Clinical Pharmacy Researcher, Department of Physiology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Pulau Pinang, Malaysia Professor Professor, Department of Clinical Pharmacy, Universiti Teknologi MARA, Puncak Alam Campus, Bandar Puncak Alam, Selangor, Malaysia Head of One Stop Centre, Clinical Research Centre, Ministry of Health, Pulau Pinang, Malaysia.
Insights
Doctors showed fair adherence to hypertension guidelines, leading to better blood pressure control. However, gaps exist in managing uncomplicated hypertension and cases with diabetes or renal disease.
Area of Science:
- Clinical Pharmacy
- Cardiovascular Medicine
- Public Health
Background:
- Suboptimal hypertension control is often linked to poor physician adherence to clinical guidelines.
- Evaluating adherence to the Malaysian Clinical Practice Guideline (CPG 2008) is crucial for improving hypertension management.
Purpose of the Study:
- To assess physician adherence to the Malaysian CPG 2008 for hypertension management.
- To identify factors associated with guideline adherence and their impact on hypertension control.
Main Methods:
- A cross-sectional study involving 26 doctors and 650 hypertensive outpatients at Hospital Pulau Pinang.
- Prescription compliance with CPG 2008 was assessed, and patient blood pressure was monitored over two visits.
- Statistical analysis using SPSS 16 was performed to determine associations.
Main Results:
- 67.1% of patients received guideline-compliant pharmacotherapy; 51% achieved goal blood pressure.
- Hypertension clinic visits were negatively associated with guideline adherence.
- Guideline adherence, ACE inhibitors positively impacted BP control, while renal disease, diabetes, and diabetic clinics showed negative associations.
Conclusions:
- A fair level of adherence to hypertension guidelines was observed, correlating with improved blood pressure control.
- Gaps in guideline implementation were noted, particularly for uncomplicated hypertension and patients with diabetes mellitus or renal disease.
Rationale, Aims And Objectives:
Existing literature suggests that doctors' poor adherence with guidelines is one of the major contributing factors to suboptimal control of hypertension. This study aims to evaluate doctors' adherence with Malaysian clinical practice guideline (CPG 2008) in a tertiary care hospital, and factors associated with guideline adherence and hypertension control.
Methods:
This was a cross-sectional study conducted at Hospital Pulau Pinang, Penang, Malaysia. Prescriptions written by 26 enrolled doctors to 650 established hypertensive outpatients (25 prescriptions per enrolled doctor) were noted on visit 1 along with patients' demographic and clinical data. The noted prescriptions were classified either as compliant or non-compliant to CPG (2008). Five hundred twenty (80%) of the enrolled patients (20 patients per enrolled doctor) were followed for one more visit. Blood pressure (BP) noted on visit 2 was related to the prescription written on visit 1. SPSS 16 (SPSS Inc., Chicago, IL, USA) was used for data analysis.
Results:
Three hundred forty-nine (67.1%) patients received guidelines compliant pharmacotherapy. In multivariate analysis, hypertension clinic had significant negative association with guidelines adherence. Two hundred sixty-five patients (51%) were at goal BP on visit 2. In multivariate analysis, angiotensin-converting enzyme inhibitors and guidelines adherence had significant positive, while renal disease, diabetes mellitus and diabetic clinic had significant negative association with hypertension control.
Conclusions:
An overall fair level of adherence with guidelines and better control of hypertension was observed. Guidelines compliant practices resulted in better control of hypertension. The gaps between what guidelines recommend and clinical practice were especially seen in the pharmacotherapy of uncomplicated hypertension and hypertension with diabetes mellitus and renal disease.
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