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Updated: May 22, 2026

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Published on: August 9, 2024
Single-session biofeedback-assisted relaxation training in children with sickle cell disease
Matthew P Myrvik1, Andrew D Campbell, Jennifer L Butcher
1Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI 53226, USA. mmyrvik@mcw.edu
Abstract:
Sickle cell disease (SCD) pain remains difficult to manage. This pilot study evaluated single-session biofeedback-assisted relaxation training (BART) for SCD pain in children. Ten participants (mean = 12.1 y) completed a 1-hour BART session using thermal biofeedback and home practice. Participants demonstrated changes in peripheral body temperature after the training session (d = 1.08) and at 6-week follow-up (d = 0.97) relative to their baseline visit. Reductions in patient-reported pain frequency were found after completing BART. Health-related quality of life and pain-related disability improvements were observed; however, effect sizes were small to minimal. Single-session BART may be a promising, complementary approach to medical management of pediatric SCD pain.

