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Marzia Martina1

  • 1Synaptic Therapies and Devices Group, Institute for Biological Sciences, National Research Council of Canada Ottawa, ON, Canada.

Frontiers in Pharmacology
|May 16, 2012
PubMed
Summary

No abstract available in PubMed .

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Patch Clamp01:18

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Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...

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