Understanding nano-anatomy of healthy and carious human teeth: a prerequisite for nanodentistry

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Updated: May 22, 2026

Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy
11:02

Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy

Published on: April 13, 2022

Sebastian Gaiser1, Hans Deyhle, Oliver Bunk

  • 1Biomaterials Science Center, University of Basel, University Hospital, 4031, Basel, Switzerland.

Biointerphases
|May 17, 2012
PubMed

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The Crown, Neck, and Root
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The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
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The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...