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Updated: May 22, 2026

11:51
Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
7-Chloro-4-[(7-chloro-quinolin-4-yl)sulfan-yl]quinoline dihydrate
Abstract:
In the title thio-ether dihydrate, C(18)H(10)Cl(2)N(2)S·2H(2)O, the S-bound quinolinyl residues are almost orthogonal, forming a dihedral angle of 72.36 (4)°. In the crystal, the four water mol-ecules are connected via an eight-membered {⋯OH}(4) synthon with each of the four pendent water H atoms hydrogen bonded to a pyridine N atom to stabilize a three-dimensional architecture.
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